unbelieavably inspiring piece. it would totally serve as a matte painting for a game (or a movie, animation, whatever). but i can see the whole thing as a game. little guy stepping up the corner of the canvas, just checking that specific part of the level with the weird clock and then... a few pre-rendered screens later, you end up on one end of that bridge above the clock, making your way to the other side, where a very interesting cutscene awaits.
dude, that's awesome. and completely done in traditional media, i suppose. really amazing.